Cancer Prev Institute publications

• Dotto et al. Androgen receptor signalling in non-prostatic malignancies: challenges and opportunities. Nat Rev Cancer. 2025.
• Mazzeo et al. ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation. Nat Commun. 2024.
• Samarkina et al. Androgen receptor is a determinant of melanoma targeted drug resistance. Nat Commun. 2023.
• Ghosh et al. Nuclear lamin A/C phosphorylation by loss of Androgen Receptor is a global determinant of cancer-associated fibroblast activation. Nat Commun. 2024.
• Koliaraki et al. Mesenchymal cells in health and disease. Nat Immunol. 2022.
• Scabia et al. Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor. Nat Commun. 2022.
• Xu et al. HSD17B7 gene in self-renewal and oncogenicity of keratinocytes from Black versus White populations. EMBO Mol Med. 2021.
• Shamseddin et al. Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation. EMBO Mol Med. 2021.
• Ma et al. Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis. J Exp Med. 2021.
• Sflomos et al. Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1. EMBO Mol Med. 2021.
• Katarkar et al. NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin. Nat Commun. 2020.
• Özdemir et al. Sex Hormones and Anticancer Immunity. Clin Cancer Res. 2019.
• Fiche et al. Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions. J Pathol. 2019.
• Clocchiatti et al. Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation. J Clin Invest. 2018.
• Özdemir et al. Sex Differences in Efficacy and Toxicity of Systemic Treatments: An Undervalued Issue in the Era of Precision Oncology. J Clin Oncol. 2018.
• Özdemir et al. The challenges of modeling hormone receptor-positive breast cancer in mice. Endocr Relat Cancer. 2018.

Sexual Dimorphism Cancer Program